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Fig. 7 | Molecular Medicine

Fig. 7

From: HOXA11-OS participates in lupus nephritis by targeting miR-124-3p mediating Cyr61 to regulate podocyte autophagy

Fig. 7

Effect of HOXA11-OS on the expression of autophagy factors and podocyte markers in kidney tissues by targeting miR-124-3p regulating Cyr61. A The expression of HOXA11-OS mRNA was detected by qRT-PCR after AAV was injected into mouse kidney tissues. B The expression of Cyr61, Beclin-1, LC3B, nephrin, and podocin in kidney tissues of mice was detected by qRT-PCR and western blotting. C The expression of Cyr61, LC3B, and nephrin in kidney tissues of mice was detected by IF. &P > 0.05, *P < 0.05 vs. sh-NC; #P < 0.05 vs. sh-HOXA11-OS; &*P < 0.05 vs. Lupus + sh-NC; ##P < 0.05 vs. Lupus + sh-HOXA11-OS. Data are presented as means ± standard deviation. Scale bars represent 15 µm

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Molecular Medicine

ISSN: 1528-3658