Fig. 5From: Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER–ERK–NF-κB signaling pathwayG15 and U0126 reversed the neuroprotective effects of ICT in tMCAO rats. A The experimental timeline. B and C The cerebral infarct volume after tMCAO in brain tissue in the different groups were analyzed by TTC staining (n = 4). D Neurological function scores. E The rotating speed in rotarod test (n = 4). F The time on rod in rotarod test (n = 4). The results are expressed as the mean ± SD, *P < 0.05, **P < 0.01, compared with tMCAO + ICT groupBack to article page