Fig. 6From: Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER–ERK–NF-κB signaling pathwayU0126 and G15 reversed the effect of ICT on reducing brain edema and neuroinflammation in tMCAO rats. A The water content of rat ischemic lateral brain tissue (n = 4). B and C IL-1β and IL-10 levels in rat brain tissue in ischemic penumbra area (n = 4). The results are expressed as the mean ± SD, *P < 0.05, **P < 0.01, compared with tMCAO + ICT groupBack to article page