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Table 1 Garcia JH Neurological Scoring Criteria for rats

From: Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER–ERK–NF-κB signaling pathway

Test

0

1

2

3

Spontaneous activity (The rat was observed for 5 min in cage)

No movement

Barely moves

Move and touching at least one side of cage

Moving and touching at least three side of cage

Limb symmetry (Observation of four limbs after rats suspended)

Left limb: no movement

Left limb: slight movement

Left limb: slowness of movements

Symmetrical extension of limbs

Symmetry of forelimbs (Lift the tail to observe forelimb movement)

Left forelimb: no movement, no outreaching

Left forelimb: slight movement to outreach

Left forelimb: moves and outstretches less than the right

Symmetry outstretch

Climbing (45° of wire climbing)

Fails to climb

Left side is weak

Climb normally, hold tight to the wire

Body proprioception

Left unresponsive

The left stimulus response was slow than that right

Both side reactions are the same

Response to vibrissae touch

Left unresponsive

The left stimulus response was slow than that right

Both side reactions are the same