Skip to main content
Fig. 1 | Molecular Medicine

Fig. 1

From: OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall’s plaque formation

Fig. 1

OCT4 and osteogenic related markers were upregulated in Randall’s plaques (RP). A Endoscopic images of normal renal papillae (NRP) and RP attached with a renal stone (black arrows). B Representative images of Von Kossa staining for calcium deposits (black granules) in NRP. C–E QRT-PCR analysis of OCT4, RUNX2, OCN mRNA expression in RP (n = 28) and NRP (n = 28). F, G Liner regression analysis of OCT4 mRNA expression and RUNX2 as well as OCN mRNA expression in RP (n = 28) and NRP (n = 28). H Representative images of IHC for OCT4, RUNX2, OCN in RP (N = 8) and NRP (N = 8). I–L Immunoblotting (IB) analysis of OCT4, RUNX2 and OCN in RP (n = 18) and NRP (n = 18). M, N Liner regression analysis of OCT4 protein density and RUNX2 as well as OCN protein density in RP (n = 18) and NRP (n = 18)

Back to article page

Molecular Medicine

ISSN: 1528-3658