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Fig. 3 | Molecular Medicine

Fig. 3

From: LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB

Fig. 3

LOTUS overexpression suppresses Aβ-induced decrease of spine density. a Representative images of dendritic spines of cultured hippocampal neurons from WT or LOTUS-tg mice after 48 h of treatment with Aβ. Scale bars, 5 μm. b Quantification of spine density of each dendrite per 10 µm. The data are presented as mean ± SEM from five independent cell culture preparations (n = 5, 5 or more cells were analyzed at each experiment, Two-way ANOVA post hoc Tukey test *p < 0.05, **p < 0.01)

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Molecular Medicine

ISSN: 1528-3658