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Fig. 4 | Molecular Medicine

Fig. 4

From: LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB

Fig. 4

Binding ability human soluble LOTUS and LilrB2. a Representative images of the binding assay using soluble human LOTUS protein (LOTUS-Fc-SBP, 500 nM) in LilrB2-overexpressing Cos7 cells and immunocytochemistry with the antibody against LilrB2. Scale bars, 100 μm. b, c Saturation curves (b) and scattered analysis (c) of binding control protein or soluble human LOTUS to LilrB2 overexpressed in Cos7 cells. The data are presented as mean ± SEM from three independent cell culture preparations (n = 3). The Kd value was estimated to be 196.1 ± 26.4 nM

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Molecular Medicine

ISSN: 1528-3658