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Fig. 4 | Molecular Medicine

Fig. 4

From: Oxidized LDL promotes EMS-induced angiogenesis by increasing VEGF-A expression and secretion by endometrial cells

Fig. 4

OxLDL increased the expression and secretion of VEGF-A in endometrial cells. A VEGF-A expression in eutopic endometrium and ectopic endometrium from the animal models treated with oxLDL (dissolved in PBS solution) or the same volume of PBS for 48 h. VEGF-A was stained by immunohistochemistry, while all the tissues were also stained by H&E and iron. B, C Western blot analysis of VEGF-A expression in the hESCs and hEECs treated with oxLDL and PBS. The histogram represents the greyscale of each lane from the Western blot. The number in each group was 3. * compared with the 0 µg/ml oxLDL group, p < 0.05. D The VEGF-A secretion of the hESCs and hEECs treated with oxLDL and PBS for 48 h was tested by ELISAs. The number in each group was 3. * compared with the 0 µg/ml oxLDL group, p < 0.05

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