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Fig. 5 | Molecular Medicine

Fig. 5

From: Oxidized LDL promotes EMS-induced angiogenesis by increasing VEGF-A expression and secretion by endometrial cells

Fig. 5

RNA-seq analysis predicted the potential mechanism by which oxLDL upregulates VEGF-A expression. A KEGG analysis of the hEECs treated with oxLDL and PBS showed the possible signalling pathway involved in the process of oxLDL upregulating VEGF-A. B Heatmap analysis predicted that VEGF-A may be upregulated by oxLDL. C–E The GSEA plot shows that VEGF-A expression positively correlates with AKT-mTOR-activated gene signatures (MA_ENDOMETRIAL_EPITHELIAL_CELL, MINTA_VASCULAR_SMOOTH_MUSCLE_CELL, YANG_BLADDER_CANCER_CELL)

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Molecular Medicine

ISSN: 1528-3658