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Fig. 2 | Molecular Medicine

Fig. 2

From: Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

Fig. 2

Nine subpopulations of FBs were identified with differential markers and functions. A t-SNE plot showed 9 subpopulations of FBs after re-clustering. B The proportion of each subpopulation of FBs between control and ATAD group. The dashed line was used to distinguish the dominant subpopulations in ATAD and control group. C Heatmap of marker genes for each subpopulation of FBs. D t-SNE plots showed the expressions of representative marker genes for each subpopulation of FBs. E The expressions of growth factors in subpopulations of FBs. F Qusage analysis of selected gene-sets enrichment relating to ATAD and FBs functions for each subpopulation of FBs. G Qusage analysis of hallmark gene-sets enrichment for each subpopulation of FBs. H the results of Qusage analysis to identify functions of contraction, collagen synthesis and proliferation for each subpopulation of FBs. I DEGs in subpopulations of FBs (ATAD/Control). J GO analysis for up-regulated and down-regulated genes in subpopulations of FBs (ATAD/Control)

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Molecular Medicine

ISSN: 1528-3658