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Fig. 3 | Molecular Medicine

Fig. 3

From: Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

Fig. 3

Nine subpopulations of ECs were obtained upon re-clustering with distinct markers and functions. A t-SNE plot showed 9 subpopulations of ECs. B The proportion of each subpopulation of ECs between control and ATAD group. The dashed line marked off the dominant subpopulations in ATAD and control group. C Heatmap of marker genes for each subpopulation of ECs. D t-SNE plots showed the expressions of representative marker genes for each subpopulation for ECs. E The expressions of growth factors for each subpopulation of ECs. F Qusage analysis of hallmark gene-sets enrichment for each subpopulation of ECs. G DEGs in subpopulations of ECs (ATAD/Control). H GO analysis for up-regulated and down-regulated genes in subpopulations of ECs (ATAD/Control)

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Molecular Medicine

ISSN: 1528-3658