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Fig. 4 | Molecular Medicine

Fig. 4

From: Single-cell transcriptomic analysis reveals differential cell subpopulations and distinct phenotype transition in normal and dissected ascending aorta

Fig. 4

Eight subpopulations of neutrophils were identified with different markers, functions and stages. A t-SNE plot showed 8 subpopulations of neutrophils upon re-clustering. B, C Qusage analysis to identify the exact stage and function for each subpopulation of neutrophils. D the proportion of each subpopulation of neutrophils between control and ATAD group. The dashed line discriminated the dominant subpopulations in control and ATAD group. E heatmap of marker genes for each subpopulation of neutrophils. F t-SNE plots to show the expressions of representative marker genes for each subpopulation of neutrophils. G Qusage analysis of hallmark gene-sets enrichment for each subpopulation of neutrophils. H the expressions of cytokines for each subpopulation of neutrophils. I DEGs in subpopulations of neutrophils (ATAD/Control). J GO analysis for up-regulated and down-regulated genes in subpopulations of neutrophils (ATAD/Control)

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Molecular Medicine

ISSN: 1528-3658