Table 1 Demographic, clinical and laboratory parameters of patients
Total (n = 105) | Patients with Delta SOFA score < 2 (n = 50) | Patients with Delta SOFA score > 2 (n = 55) | p value | |
|---|---|---|---|---|
Gender, male | 50 (47.62%) | 27 (54.00%) | 23 (41.82%) | 0.24 |
Gender, female | 55 (52.38%) | 23 (46.00%) | 32 (58.18%) | |
Age (years) | 50.00 (37.50–57.50) | 54.50 (39.00–58.00) | 47.00 (35.00–55.00) | 0.17 |
Etiologic agent (%) | ||||
Escherichia coli | 61 (58.10%) | 28 (56.00%) | 33 (60.00%) | 0.36 |
Klebsiella pneumoniae | 12 (11.43%) | 7 (14.00%) | 5 (9.09%) | |
Pseudomonas aeruginosa | 12 (11.43%) | 8 (16.00%) | 4 (7.27%) | |
Site of infection (%) | ||||
Abdominal | 71 (67.62%) | 32 (64.00%) | 39 (70.91%) | 0.15 |
Urinary tract | 20 (19.05%) | 12 (24.00%) | 8 (14.55%) | |
Intravenous catheter | 5 (4.76%) | 3 (6.00%) | 2 (3.64%) | |
Pulmonary | 4 (3.81%) | 0 (0.00%) | 4 (7.27%) | |
Comorbidities | ||||
Dyslipidemia | 61 (58.10%) | 32 (64.00%) | 29 (52.73%) | 0.89 |
Immunosuppression | 55 (52.38%) | 26 (52.00%) | 29 (52.73%) | |
Cancer | 55 (52.38%) | 28 (56.00%) | 27 (49.09%) | |
Liver dysfunction | 27 (25.71%) | 12 (24.00%) | 15 (27.27%) | |
Laboratory tests | ||||
CRP (mg/L) | 14.00 (7.30–19.80) | 10.75 (4.80–16.87) | 15.20 (9.47–21.50) | < 0.05 |
PCT (ng/mL) | 7.40 (1.80–17.90) | 3.10 (1.33–8.58) | 11.40 (3.90–24.33) | < 0.01 |
Hemoglobin (g/dL) | 10.27 ± 2.63 | 10.38 ± 2.62 | 10.17 ± 2.66 | 0.47 |
Serum Albumin (g/dL) | 3.17 ± 0.73 | 3.26 ± 0.70 | 3.09 ± 0.76 | 0.23 |
Total bilirubin (mg/dL) | 1.40 (0.62–4.90) | 0.90 (0.60–2.93) | 2.20 (0.90–7.40) | < 0.01 |
Lactate (mmol/L) | 2.40 (1.40–4.00) | 1.65 (1.18–2.60) | 3.45 (1.63–4.20) | < 0.01 |
Creatinine (mg/dL) | 0.90 (0.65–1.40) | 0.80 (0.50–1.06) | 1.00 (0.70–1.90) | < 0.01 |
White blood cells (× 109/L) | 6.95 (0.35–12.30) | 7.25 (0.60–12.18) | 6.65 (0.10–12.30) | 0.87 |
Platelet (× 103/µL) | 107.0 (21.00–243.00) | 162.50 (26.25–265.00) | 100.00 (16.00–216.00) | 0.19 |
HDL (mg/dL) | 35.19 ± 17.71 | 36.88 ± 17.57 | 33.65 ± 17.89 | 0.40 |
Total cholesterol (mg/dL) | 138.50 (113.30–181.80) | 139.50 (109.00–201.30) | 136.00 (115.80–165.50) | 0.56 |
LDL (mg/dL) | 75.00 (48.25–109.30) | 77.00 (48.75–118.30) | 73.00 (47.50–101.50) | 0.46 |
Delta SOFA score | 0–11 | 0–1 | 2–11 | |