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Table 1 Basic characteristics of the study groups

From: MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin

 

Controls (n = 61)

ALL (n = 66)

p-value

Sex, F/M ratio

1.34

1.35

0.981

Age, years

23 (18–42)

22 (18–38)

0.056

Creatinine (µmol/l)

76 (48–118)

68 (42–97)

9.0E−3

Total cholesterol (mmol/l)

4.50 (2.49–6.60)

4.2 (3.1–5.9)

0.146

HDL (mmol/l)

1.71 (0.93–2.66)

1.67 (0.93–2.79)

0.362

LDL (mmol/l)

2.69 (1.02–4.89)

2.2 (1.2–4.1)

1.5E−4

Triglycerides(mmol/l)

0.94 (0.31–3.49)

0.80 (0.34–2.40)

1.4E−3

RBC (10/µl)

4.95 (4.06–5.92)

4.98 (4.02–5.68)

0.877

Hemoglobin (g/dl)

14.1 (12.1–17.1)

14.95 (12.50–16.90)

0.100

Hematocrit (%)

42.5 (37.0–51.1)

43.5 (36.0–47.7)

0.794

MCV (fl)

87.1 (75.5–94.1)

87.4 (79.0–94.3)

0.639

MCH (pg)

29.2 (24.4–31.8)

29.9 (26.2–33.2)

2.0E−03

MCHC (g/dl)

33.3 (31.3–35.3)

34.4 (32.2–36.5)

1.8E−08

Platelets (103/µl)

321 (147–377)

266 (168–415)

0.547

MPV (fl)

8.0 (4.3–10.1)

10.7 (8.8–12.7)

< 2.2E−16

White blood cells (103/µl)

5.88 (4.04–11.30)

5.48 (2.64–13.04)

0.426

Neutrophils (103/µl)

3.40 (1.83–7.00)

3.05 (1.20–12.20)

0.483

Lymphocytes (103/µl)

1.7 (1.1–2.7)

1.6 (0.3–3.2)

0.066

Monocytes (103/µl)

0.5 (0.22–1.00)

0.5 (0.2–1.1)

0.516

Eosinophils (103/µl)

0.1 (0.0–0.7)

0.1 (0.0–0.5)

0.090

Basophils (103/µl)

0.0 (0.0–0.1)

0.0 (0.0–0.1)

0.010

  1. The median (range) values are reported; the p-value corresponds to the Fisher’s exact test or Wilcoxon signed-rank test for equality of location parameters in the two groups. P-values marked with bold indicate statistically significant (p-value < 0.05) differences between the groups.
  2. HDL high-density lipoproteins, LDL low-density lipoproteins, RBC red blood cells, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, MPV mean platelet volume
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Molecular Medicine

ISSN: 1528-3658