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Table 2 The top 10 differentially expressed miRNAs between controls and ALL survivors in blood plasma (top panel), EVs (middle panel) and differentially distributed between these compartments (bottom panel)

From: MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin

miRNA

Precursor

logFC

logCPM

p-value

FDR

Plasma

 miR-184

mir-184

− 5.358

8.897

2.49E−16

4.95E−13

 miR-324-5p

mir-324

− 3.276

1.897

4.62E−10

4.59E−07

 miR-4753-5p

mir-4753

− 3.149

1.352

2.08E−09

1.05E−06

 let-7g-5p

let-7g

− 0.701

13.642

2.11E−09

1.05E−06

 miR-579-5p

mir-579

− 3.385

1.968

4.17E−09

1.66E−06

 miR-1-3p

mir-1-2

− 2.993

7.536

6.95E−09

2.16E−06

 miR-1-3p

mir-1-1

− 2.973

7.480

7.61E−09

2.16E−06

 miR-3140-3p

mir-3140

− 3.108

1.629

1.88E−08

4.67E−06

 miR-3939

mir-3939

− 2.335

1.270

2.82E−07

6.21E−05

 miR-1273c

mir-1273c

4.799

3.364

4.13E-07

8.21E−05

EVs

 miR-221-5p

mir-221

3.766

4.657

3.26E−11

6.48E−08

 miR-199a-3p

mir-199a-2

1.722

9.299

9.30E−10

4.63E−07

 miR-199b-3p

mir-199b

1.722

9.298

9.31E−10

4.63E−07

 miR-199a-3p

mir-199a-1

1.722

9.298

9.32E−10

4.63E−07

 miR-203a-3p

mir-203a

3.924

5.776

1.45E−09

5.77E−07

 miR-574-5p

mir-574

3.101

3.979

1.48E−08

4.89E−06

 miR-148a-5p

mir-148a

− 2.639

5.911

2.00E−08

5.68E−06

 miR-200a-3p

mir-200a

2.288

8.178

2.78E−08

6.89E−06

 miR-145-5p

mir-145

6.219

4.239

3.27E−08

7.21E−06

 miR-378i

mir-378i

1.891

6.074

1.07E−07

2.13E−05

Differentially distributed between plasma and EVs

 miR-184

mir-184

− 6.218

8.897

7.60E−14

1.51E−10

 miR-1-3p

mir-1-2

− 5.072

7.536

1.19E−12

1.18E−09

 miR-1-3p

mir-1-1

− 4.935

7.480

3.52E−12

2.33E−09

 miR-548am-5p

mir-548am

7.756

3.824

3.68E−08

1.75E−05

 miR-548o-5p

mir-548o-2

7.625

3.824

5.56E−08

1.75E−05

 miR-548c-5p

mir-548c

7.625

3.824

5.58E−08

1.75E−05

 miR-208b-3p

mir-208b

7.869

1.993

6.18E−08

1.75E−05

 miR-199b-3p

mir-199b

− 1.982

9.298

4.26E−07

9.02E−05

 miR-199a-3p

mir-199a-1

− 1.982

9.298

4.26E−07

9.02E−05

 miR-199a-3p

mir-199a-2

− 1.977

9.299

4.54E−07

9.02E−05

  1. logFC log fold change, logCPM log counts per million, FDR false discovery rate
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Molecular Medicine

ISSN: 1528-3658