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Fig. 1 | Molecular Medicine

Fig. 1

From: Hypolipidemic effect of ethanol extract from Chimonanthus nitens Oliv. leaves in hyperlipidemia rats via activation of the leptin/JAK2/STAT3 pathway

Fig. 1

Effects of COE on body weight, hepatic wet weight and liver index in HFD-treated rats. A Body weight was measured at the end of the experimental period. B Hepatic wet weight was determined after COE or SIM treatment. C The liver index was assessed after COE or SIM treatment. D Histopathological changes in the liver of rats observed by H&E staining (black arrow indicated fat vacuole infiltration). NMD, normal diet. HFD, high-fat diet. SIM, simvastatin. COE, ethanol extract of Chimonanthus nitens Oliv. leaf. COE-L, COE at the low dose, COE-M, COE at the medium dose. COE-H, COE at the high dose. n = 8; *P < 0.05, **P < 0.01, ***P < 0.001 vs. NMD or HFD rats

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Molecular Medicine

ISSN: 1528-3658