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Table 2 Effect of TOP2A-inhibitor on mouse preimplantation embryo development

From: TOP2A deficiency leads to human recurrent spontaneous abortion and growth retardation of mouse pre-implantation embryos

Group

Developmental rate of four-cell(%)

Developmental rate of blastocysts(%)

M16

85.34

56.89

TOP2A-inhibitor

59.60

34.46

P

 < 0.001

 < 0.001

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Molecular Medicine

ISSN: 1528-3658