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Fig. 1 | Molecular Medicine

Fig. 1

From: Bone marrow mesenchymal stem cell-derived exosomal lncRNA KLF3-AS1 stabilizes Sirt1 protein to improve cerebral ischemia/reperfusion injury via miR-206/USP22 axis

Fig. 1

The role of Exos-KLF3-AS1 in MCAO mice. Mice were subjected to MCAO surgery, followed by injected intravenously with sdyExos, Exos-vector or Exos-KLF3-AS1. A Neurological severity scores of mice. B, C The active avoidance behavior of mice by shuttle box test. D Infarct volume was calculated. Sirt1 expression detected by immunohistochemistry (E) and western blot (F). n = 5 per group. Data are described as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658