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Fig. 2 | Molecular Medicine

Fig. 2

From: Bone marrow mesenchymal stem cell-derived exosomal lncRNA KLF3-AS1 stabilizes Sirt1 protein to improve cerebral ischemia/reperfusion injury via miR-206/USP22 axis

Fig. 2

The role of Exos-KLF3-AS1 in OGD exposed cells in vitro. Cells were subjected to OGD followed by treated with PBS or Exos-KLF3-AS1. A Cell viability determined by MTT. B Cell apoptosis assessed with TUNEL assay. C ROS production determined by ROS assay. D, E The mRNA and protein levels of MCP-1, TNFα and IL-6 detected using qRT-PCR and western bolt. F Sirt1 protein expression detected by western bolt. Values were expressed as mean ± SD of three separate determinations in the in vitro assays. *P < 0.05, **P < 0.01, ***P < 0.001

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