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Fig. 1 | Molecular Medicine

Fig. 1

From: LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

Fig. 1

LINC00963 was up-regulated and positively associated with worse prognosis of LUAD patients. A LINC00963 expression levels were examined by RT-qPCR between 60 pairs of LUAD tissues and matching noncancerous lung tissues. B The expression level of LINC00963 tested in A was presented with each individual patient. C The overall survival was analyzed between LUAD patients presenting high (n = 45) and low (n = 15) LINC00963 expression using Kaplan-Meier method. D LINC00963 expression was compared between LUAD tissues of higher (III + IV; n = 41) and lower (I + II; n = 19) TNM stages. E LINC00963 expression was compared between non-metastatic (n = 26) and metastatic (n = 34) LUAD tumors. F LINC00963 expression was examined by RT-qPCR in lung epithelial cell line BEAS-2B and six LUAD cell lines, NCI-H1975, NCI-H1299, A549, Calu-3, NCI-H358 and NCI-H1650. G, H FISH analysis of LINC00963 in LUAD tissues (G), and in A549 and NCI-H1650 cells (H). *P < 0.05, **P < 0.01 and ***P < 0.001

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