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Fig. 3 | Molecular Medicine

Fig. 3

From: LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

Fig. 3

LINC00963 significantly induced the migration, invasion, and EMT of LUAD cells. A549 and NCI-H1650 cells stably expressed two distinct shRNA targeting LINC00963 or overexpressed LINC00963. A Cell migration and invasion were assessed by Transwell assays. B Expression levels of E-cadherin, N-cadherin, and vimentin were examined by western blot. C E-cadherin (green) and N-cadherin (red) were detected by immunofluorescence and the nuclei were stained by DAPI (blue) in indicated cells. Scale bar: 50 μm. *P < 0.05, **P < 0.01 and ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658