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Fig. 7 | Molecular Medicine

Fig. 7

From: LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

Fig. 7

LINC00963 physically interacted with HNRNPA2B1 protein. A The potential interaction between LINC00963 and Zeb1 protein was assessed by RIP assay using anti-Zeb1 or IgG (negative control) antibody. B The potential interaction between HNRNPA2B1, LINC00963, and Siah1 mRNA was examined by RIP assay using anti-HNRNPA2B1 and IgG (negative control) antibody. C RNA pull-down assay verified the interaction between LINC00963 and HNRNPA2B1 protein. D RT-qPCR measured HNRNPA2B1 expression between 60 pairs of LUAD tissues and matching noncancerous lung tissues. E The association between LINC00963 and HNRNPA2B1 levels in 60 LUAD tissues was analyzed by Pearson correlation analysis. F HNRNPA2B1 expression in indicated cells was examined by western blot. n.s., not significant, *P < 0.05, **P < 0.01 and ***P < 0.001

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