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Fig. 9 | Molecular Medicine

Fig. 9

From: LINC00963 promotes the malignancy and metastasis of lung adenocarcinoma by stabilizing Zeb1 and exosomes-induced M2 macrophage polarization

Fig. 9

Macrophages pre-conditioned with exosomal LINC00963 promoted LUAD growth and metastasis in vivo. A549 cells, together with macrophages pre-treated with exosomes isolated from indicated A549 cells, were subcutaneously injected into nude mice. Photographs (A), growth curve (B), and weight (C) of xenografts from indicated groups. D Immunohistochemistry staining of Ki-67, Zeb1, and CD206 from indicated xenograft tumors. Scale bar: 50 μm. *P < 0.05 and ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658