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Table 2 Study population

From: Evaluation of inherited germline mutations in cancer susceptibility genes among pancreatic cancer patients: a single-center study

 

PanC (No. 47)

CS (No. 51)

Gender, N (%)

  

 Male

25 (53.2)

58 (54.9)

 Female

22 (46.8)

23 (45.1)

Age, median (IQR)

60 (49–68)

63 (57–68)

 < 55 years, N (%)

24 (51.1)

9 (17.6)

 ≥ 55 years, N (%)

23 (48.9)

42 (82.4)

Body Mass Index, N (%)*

  

 ≤ 30

40 (87)

40 (78.4)

 > 30

6 (13)

11 (21.6)

Smoker, N (%)

  

 No

12 (25.5)

17 (33.3)

 Current

17 (36.2)

21 (41.2)

 Past

18 (38.3)

13 (25.5)

Alcohol intake, N (%)

  

 No

16 (34)

16 (31.4)

 Moderate

27 (57.5)

28 (54.9)

 Heavy

4 (8.5)

7 (13.7)

Diabetes, N (%)

  

 No

31 (66)

24 (47.1)

 Yes

16 (34)

17 (52.9)

 Early-Onset

7 (43.8)

16 (59.3)

Family history of cancer, N (%)*

  

 Pancreas

25 (53.2)

20 (40)

 Breast

7 (14.9)

4 (8)

 Endometrium

6 (12.8)

0

 Colon

5 (10.6)

6 (12)

 Melanoma

2 (4.3)

1 (2.0)

 Other

19 (40.4)

13 (26)

Pre-operative classification, N (%)*

  

 Resectable

11 (24.4)

 

 Locally advanced

15 (33.3)

 

 Metastatic

19 (42.2)

 

Surgery, N (%)*

  

 No

32 (69.6)

 

 Yes

14 (30.4)

 

Tumor location, N (%)*

  

 Head

35 (79.5)

 

 Body/Tail

9 (20.5)

 

Tumor stage, N (%)*

  

 IA

1 (2.3)

 

 IIB

14 (31.8)

 

 III

8 (18.2)

 

 IV

21 (47.7)

 

Adjuvant therapy, N (%)*

  

 No

9 (20.5)

 

 Yes

35 (79.5)

 
  1. *Variables with some missing data. PanC: pancreatic cancer; CS: control subjects