Fig. 1

Different METTL3 expression and m⁶A levels in the placentas from preeclamptic and healthy pregnant women. A The different m⁶A levels determined by m⁶A colorimetric assay. B The different METTL3 mRNA levels detected by qRT-PCR. C–F Representative WB images and densitometry quantification of METTL3, GRP78 and CHOP. The data were normalized to β-actin. G METTL3 expression determined by IHC. Photographs were obtained at 100 × (up, Scale bar 100 μm) and 200 × (down, Scale bar 50 μm) magnification. H Qualified data shown in G. H Healthy Pregnant Women; P: Preeclamptic Pregnant Women. n = 3. ns: no significance, *p < 0.05, **p < 0.01, ***p < 0.001