Fig. 4

Behavioral responses to thermal and mechanical stimuli on hind paws. The hind paw withdrawal response to A thermal hyperalgesia and B mechanical allodynia was assessed at day 0 (baseline); weekly for two months after intrathecal injection of AAV-GlyRα3 (2.5 × 10¹² vg), AAV (2.5 × 10¹² vg), or NaCl; and daily for four days after CFA (100 μl) injection. Mann–Whitney U test, **p < 0.01, ***p < 0.001 (used in comparison between GNF and Gα3F groups). ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 (used in comparison between GVF and Gα3F groups); D, days