Fig. 6
Effects of AAV-GlyRα3 on the expression level of cytokines in the L5 DRGs of CFA‑treated rats. For this experiment, CFA (100 μg/100 μl) hind paw injection was administered 8 weeks after the intrathecal injection of AAV-GlyRα3 (2.5 × 1012 vg). After 2 days of CFA treatment, L5 DRGs (25 μg/100 μl) were collected to evaluate cytokines expression. By ELISAs, the expression of A TNF-α, B IL-1β and C IL-6 was determined. The results are expressed as the means ± SE, and the data shown represent from three to five independent experiments. Mann–Whitney U test was used. *p < 0.05, **p < 0.01, ***p < 0.001