Fig. 4
From: An engineered miRNA PS-OMe miR130 inhibits acute lung injury by targeting eCIRP in sepsis
PS-OMe miR130 decreases systemic injury and inflammation. Blood was collected from sham, vehicle (veh), and PS-OMe miR130 (miR) treated mice at 20 h after CLP. A Serum LDH was determined using specific colorimetric enzymatic assays. Serum B TNF-α, C IL-6, and D IL-1β were measured by ELISA (n = 8–10/group). For A data expressed as means ± SEM and compared by Kruskal–Wallis test with Dunn’s method (*P ≤ 0.05 versus sham; #P ≤ 0.05 vs. veh). All other data expressed as means ± SEM and compared by one-way ANOVA and SNK method (*P ≤ 0.05 versus sham; #P ≤ 0.05 vs. veh)