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Fig. 3 | Molecular Medicine

Fig. 3

From: Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model

Fig. 3

Expression of Yes-associated protein (YAP), phosphorylated (p)-YAP, transcription coactivator with PD2-binding motif (TAZ) and p-TAZ in IMR-90 cells, ex vivo fetal lungs, and fibroblasts of ex vivo fetal lungs by lipopolysaccharide (LPS). A Expressions of YAP, p-YAP, p-YAP/YAP, TAZ, p-TAZ, and p-TAZ/TAZ in IMR-90 cells by LPS at 0, 10, 30, and 50 μg/ml for 24 h (n = 6). B Expressions of YAP, p-YAP, p-YAP/YAP, TAZ, p-TAZ, and p-TAZ/TAZ in whole fetal lungs by LPS at 0, 10, 30, and 50 μg/ml for 3 days (n = 6). C Expressions of fibronectin+ YAP, p-YAP, p-YAP/YAP, TAZ, p-TAZ, and p-TAZ/TAZ of fetal lungs by LPS at 0 and 50 μg/ml for 3 days. DAPI (in blue) marked nuclear staining. Fibronectin (in red). YAP, p-YAP, TAZ, and p-TAZ (in green) (n = 3). *p < 0.05

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