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Fig. 7 | Molecular Medicine

Fig. 7

From: Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model

Fig. 7

Summary. High dose LPS exposure induced the inflammatory response and led to YAP/TAZ phosphorylation in fibroblast of fetal lungs in pseudoglandular stage. FGF10 secreted by mesenchyme, proximal and distal airway markers SOX2 and SOX9 expression decreased branching and caused abnormal branching. Phosphorylation of anti-apoptotic factor SIRT1 after exposure to LPS might be associated with mitigating the injury from inflammation

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Molecular Medicine

ISSN: 1528-3658