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Fig. 4 | Molecular Medicine

Fig. 4

From: RBM15 suppresses hepatic insulin sensitivity of offspring of gestational diabetes mellitus mice via m6A-mediated regulation of CLDN4

Fig. 4

General features of m6A methylation in livers of offspring of GDM mouse and controls. a Venn diagram showing the overlap of m6A peaks in two groups. b The motif research for m6A-containing peak regions. c The distribution of differential Peaks on gene functional elements. d The starplot showed the genes with both differential (hyper or hypo) m6A peaks (Y axis; P < 0.05) and differential (up or down) expression (X axis; P < 0.05) in GDM group compared with control group. e The gene ontology for the hypo-up, hyper-up, hypo-down and hyper-down regulated genes. f Bar plot showing the top twenty enrichment scores of the significant enrichment pathway for the hypo-up, hyper-up, hypo-down and hyper-down regulated genes

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Molecular Medicine

ISSN: 1528-3658