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Fig. 9 | Molecular Medicine

Fig. 9

From: Exosomal IRF1-loaded rat adipose-derived stem cell sheet contributes to wound healing in the diabetic foot ulcers

Fig. 9

Schematic representation of the molecular mechanisms whereby IRF1-exosome loaded into the rASC sheet affects foot wound healing in DM rats. IRF1 loaded into the rASC sheet can induce miR-16-5p expression and target SP5, consequently promoting fibroblast proliferation and migration and endothelial cell angiogenesis and accelerating foot wound healing in DM rats

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Molecular Medicine

ISSN: 1528-3658