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Fig. 1 | Molecular Medicine

Fig. 1

From: BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity

Fig. 1

IDD occurs in STZ-induced T1DM rats. A Representative X-ray images of IVDs of normal and STZ-induced T1DM rats. B DHI measurement of normal and STZ-induced T1DM rats. C HE staining of NP tissues. NP: nucleus pulposus. D Safranin O-fast green staining for NP tissues and AF tissues. AF: annulus fibrosus. E IHC analysis of ECM-related gene expression in rat NP tissues. n = 12. *p < 0.05 vs. normal rats. Data are shown as the mean ± standard deviation. Data between two groups were compared by unpaired t-test

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