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Fig. 5 | Molecular Medicine

Fig. 5

From: Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification

Fig. 5

Potential target genes and PPI network map of KuA for OP. A The Venn results of potential genes of KuA therapy for OP. B Counts and lists of the top genes of PPI network map. C The PPI network map of 24 target genes. 723 protein nodes and 8743 edges were obtained for intersection genes. After screening with DC > 61 and a BC range of 20–113.2, the first 20 proteins were selected in Table 5 (in descending order of degree), with a total of 322 edges. PPI: Protein–Protein Interaction; KuA: Kukoamine A; OP: osteoporosis

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