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Fig. 8 | Molecular Medicine

Fig. 8

From: Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification

Fig. 8

KuA protects against cell apoptosis and oxidative stress level in OVX mice. A mRNA expression in the tibia. B Bax/BCL-2 level. C The original membrane of the western blotting. D cytochrome c level. E Caspase-3. F MnSOD. G CuZnSOD. H H2O2 level. *P < 0.05, **P < 0.01,***P < 0.001,****P < 0.0001. KuA: Kukoamine A; OVX: ovariotomy; Bax: BCL2 Associated X, Apoptosis Regulator; BCL2: BCL2 Apoptosis Regulator; SOD, Superoxide Dismutase; MDA: malondialdehyde

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