Fig. 2From: The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectivesMolecular targets and pathways involving tumor promoter and tumor suppressive activities of NEDD4 E3 ubiquitin ligases, including NEDD4-1 (A), NEDD4-L (B), SMURFs (C), WWP1 (D), and ITCH (E)Back to article page