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Fig. 2 | Molecular Medicine

Fig. 2

From: Gene expression variability in long-term survivors of childhood cancer and cancer-free controls in response to ionizing irradiation

Fig. 2

Heat maps of genes with functional interest: which were A classified both as hyper- and hypo-variable in any data set and B associated with the GO term response to radiation and -showed a classification range from to hyper-variable across all donor groups. Genes in A were additionally filtered for genes found in the RadAtlas database for radiation-associated genes, genes associated with DNA repair functions, or that were annotated to the Gene Ontology (GO) terms response to stress or response to radiation (see facet Candidate List). N0 = fibroblasts of cancer-free controls, N1 = fibroblasts of childhood cancer survivors without a second primary neoplasm, and N2 +  = fibroblasts of childhood cancer survivors with at least one second primary neoplasm

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Molecular Medicine

ISSN: 1528-3658