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Fig. 6 | Molecular Medicine

Fig. 6

From: Mesenchymal stem cells reversibly de-differentiate myofibroblasts to fibroblast-like cells by inhibiting the TGF-β-SMAD2/3 pathway

Fig. 6

Annotation of the targeted genes during uMSC-mediated MFB de-differentiation. A Venn diagrams depicting the number of DEGs regulated in MFB (MFB vs. FB) and then reversely regulated in co-cultured MFB (co-cultured MFB vs. MFB). B Enriched gene ontology analysis (EGO) concerning biological process (BP), molecular function (MF), and cellular component (CC) using the targeted DEGs. C–E Unsupervised clustering heatmap on genes participating in macroautophagy, response to TGF-β1, and collagen fibril organization in FB, MFB, and co-cultured MFB samples

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Molecular Medicine

ISSN: 1528-3658