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Fig. 4 | Molecular Medicine

Fig. 4

From: Targeting CLDN6 in germ cell tumors by an antibody-drug-conjugate and studying therapy resistance of yolk-sac tumors to identify and screen specific therapeutic options

Fig. 4

The molecular resistance mechanisms in YST. A Densitometric evaluation of relative pixel intensities of the most prominent phosphorylation sites in cell lysates from GCT72-R cells in comparison to the parental cell line, as evaluated by the human phospho-kinase array. B PCA plot, C Pearson’s correlation plot and D Volcano plot of mass-spectrometry data of FFPE-embedded YST(-R) tissues. E Enrichment plots showing gene ontology terms found exclusively in YST-R tissues. F STRING interaction analysis of YST-R-specific proteins

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Molecular Medicine

ISSN: 1528-3658