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Fig. 8 | Molecular Medicine

Fig. 8

From: Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway

Fig. 8

A proposed scheme demonstrating the protective effect of C3G against AKI. C3G decreased free iron accumulation and lipid peroxidation products, increased the levels of GSH and the expression of GPX4 and downregulated the expression of ACSL4 to inhibit ferroptosis in the renal tubular epithelial cells during AKI, which is dependent on the activation of AMPK

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