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Fig. 7 | Molecular Medicine

Fig. 7

From: Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation

Fig. 7

RIPK2 can interact with RIPKs family members and PRKCI, and participate in autophagy. A mRNA expression of RIPKs family members. B The effects of RIPK2 expression on autophagy, and autophagy on the expression of RIPK2. C Coimmunoprecipitation of RIPK2 and PRKCI. D Colocalization assay of RIPK2 and PRKCI by immunofluorescence. E PKC iota inhibition (PKCi) can decrease pancreatic cell viability. F Expression and survival analyses of PRKCI in pancreatic cancer through GEPIA database. *p < 0.05, **p < 0.01, ***p < 0.001

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