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Fig. 6 | Molecular Medicine

Fig. 6

From: Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

Fig. 6

MIR22HG knockdown suppresses osteogenic differentiation via targeting miR-128. (A) Alizarin Red staining was carried out to assess the matrix mineralization of BMSCs with different treatments. (B) ALP activity of BMSCs was measured by commercial kit. (C-H) qRT-PCR and Western blot analysis of the mRNA and protein levels of OCN, BMP2, OPN, and RUNX2 in BMSCs. * P < 0.05, ** P < 0.01 and *** P < 0.001

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