Skip to main content
Fig. 9 | Molecular Medicine

Fig. 9

From: Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

Fig. 9

Delivering of myoblast-derived exosomal Prrx-2 represses bone loss via regulating MIR22HG/miR-128/YAP axis. (A) Decalcified femurs of mice were subjected to HE staining. (B-D) BV/TV, Tb.N, and Tb.Th were detected by micro-CT. (E-G) qRT-PCR analysis of Prrx-2, MIR22HG, and miR-128 expression levels in mouse femurs. (H&I) Western blotting analysis of Prrx-2 and YAP1 protein levels in mouse femurs. * P < 0.05, ** P < 0.01 and *** P < 0.001

Back to article page

Molecular Medicine

ISSN: 1528-3658