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Fig. 2 | Molecular Medicine

Fig. 2

From: ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response

Fig. 2

Increased ATF5/HSP60/LONP1 expression in the kidneys of db/db mice and the correlation with tubular damage. A IHC staining of ATF5, HSP60, LONP1, FN and C-CAS3 in the kidney sections of 12/16-week-old db/db mice. Scale bar: 30 μm. B1–B4 The correlations of HSP60, LONP1, FN, C-CAS3 with ATF5 expression in the kidney of db/db mice. C Western blot analysis of ATF5 and HSP60, LONP1, FN, C-CAS3 in mice kidney tissue. C1–C5 Relative band density. All data are presented as means ± SD; *p < 0.05 vs db/m. r: correlation coefficient. n = 6

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Molecular Medicine

ISSN: 1528-3658