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Fig. 4 | Molecular Medicine

Fig. 4

From: ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response

Fig. 4

Upregulated expression of ATF5/HSP60/LONP1, FN/C-CAS3 in the kidney sections of db/db mice was attenuated by injection of ATF5 LV-shRNA. A Representative IHC images of ATF5, HSP60, LONP1, FN, C-CAS3 in the kidneys of mice. Scale bar: 30 μm. B Western blot analysis of ATF5, HSP60, LONP1, FN, C-CAS3. B1–B5 Relative band density of ATF5, HSP60, LONP1, FN, C-CAS3. All data are presented as means ± SD; *p < 0.05 vs. db/m; #p < 0.05 vs. db/db + LV-NC-shRNA. n = 6

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Molecular Medicine

ISSN: 1528-3658