Fig. 5
From: TRIM37 exacerbates hepatic ischemia/reperfusion injury by facilitating IKKγ translocation
Downregulation of TRAF6 abrogated TRIM37-induced hepatic inflammation. A, B Protein expression of the IKK pathway after interfering with TRAF6. C, D Protein expression of TAK1 after interfering with TRAF6. E, F Immunofluorescence analysis of p-IKK, p-p65 and F4/80 in primary Kupffer cells derived from I/R-treated liver, scale bar = 50 μm for immunofluorescence. G Liver enzymes in mouse serum after TRAF6 suppression. H The expression of apoptosis-related proteins in liver tissue after restraining TRAF6 in vivo. I, J Cytokines and chemokines in mice. N.Sp > 0.05, *p < 0.05, **p < 0.01. Two lanes in a row are from the same mixed samples, n = 5–6 for each group