Fig. 6
From: TRIM37 exacerbates hepatic ischemia/reperfusion injury by facilitating IKKγ translocation
Inhibition of the TRAF6-induced K63 chain only partially rescued hepatic I/R injury under TRIM37 amplification. A, B Hepatic pathological changes and apoptosis after C25-140 treatment or TRAF6 inhibition. Scale bar = 200 μm for HE, scale bar = 100 μm for TUNEL. C The expression of apoptosis-related proteins in liver tissue after restraining C25-140 utilization in vivo. D Levels of cytokines in mouse serum. E Levels of chemokines in the liver. N.Sp > 0.05, *p < 0.05. Two lanes in a row are from the same mixed samples, n = 5–6 for each group