Fig. 9From: CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathwaysPutative mechanisms of CIRP−/− on aggravating apoptosis in renal tubular epithelial cell during hypothermic ischemia–reperfusion injury. The diagrams of cytomembrane, nucleus and complete mitochondria was provided by Servier Medical Art (https://smart.servier.com) under CC BY 3.0 licenseBack to article page