Fig. 1
From: Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation
Nr4a1 is elevated in the kidney of UUO mice (A) Renal pathological analysis by H&E staining, Masson staining and PAS staining (400x, Bar: 50 μm). (B) Immunohistochemical staining of the expression of fibrotic proteins Fn, Col-I and Nr4a1 and (C-E) semi-quantitative analysis of positive areas. (F-G) Correlation analysis of Nr4a1expression with Fn and Col-I expression. (H) Western blot analysis of Nr4a1 expression in kidney tissues and (I) corresponding quantitative analysis. Unpaired t test was used to compare the statistical differences among sham and UUO 7d groups. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001