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Fig. 1 | Molecular Medicine

Fig. 1

From: DYNLT1 promotes mitochondrial metabolism to fuel breast cancer development by inhibiting ubiquitination degradation of VDAC1

Fig. 1

DYNLT1 is a novel therapeutic target for breast cancer and promotes breast cancer development

A Differential expression of DYNLT1 in breast tumor tissues and normal tissues. B Survival rate of breast cancer patients in high and low DYNLT1 expression group. C Analysis of DYNLT1 expression in different subtypes of breast cancer. D Relative mRNA levels of DYNLT1 in different subtypes of breast cancer cells. E Protein levels of DYNLT1 in different subtypes of breast cancer cells. On the right are statistics of the protein gray value ratio of DYNLT1/GAPDH. F-H Examination on tumors formed by stable DYNLT1 knockdown 4T1 cells in Balb/c mice: (F) Representative pictures of tumors derived from mice; (G, H) Tumor growth from mice with indicated treatment. **, p < 0.01; ***, p < 0.001; ****, p < 0.0001. All experiments were performed at least three replicates

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Molecular Medicine

ISSN: 1528-3658